The closest subway line to Cafe Sha-Sha is the red 1-9 line.
Take either the 1 or the 9 train to the Christopher Street-Sheridan Square station. You will be at the intersection of 7th Avenue South and Christopher Street.
Walk down Christopher Street (westward) until you hit Hudson. Turn right at Hudson and it should be a half block walk until you hit Cafe Sha-Sha (on the west side of the street).
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